Amiodarone-induced thyrotoxicosis with thyroid papillary cancer in multinodular goiter: case report.
نویسندگان
چکیده
OBJECTIVE To report a case of amiodarone-induced thyrotoxicosis (AIT) concomitant with thyroid cancer in multinodular goiter (MNG). CLINICAL PRESENTATION AND INTERVENTION A 61-year-old man treated with amiodarone for 5 years presented with mild sweating. He was found to have AIT simultaneously with thyroid papillary cancer and MNG. Administration of amiodarone was stopped, and he was treated with methimazole for AIT. Five weeks after the initial treatment, thyroid function normalized. Total thyroidectomy was considered to enable use of amiodarone again. CONCLUSION This case showed that thyrotoxicosis, MNG and amiodarone may contribute to thyroid carcinogenesis. Amiodarone should be carefully commenced in cases with MNG.
منابع مشابه
Surgical management of hyperthyroidism.
AIMS Hyperthyroidism includes several clinical and histopathological situations. Surgery is commonly indicated after failure of medical treatment. The aim of this study was to analyze the indications and complications of surgery as well as endocrine results. MATERIALS AND METHODS Patients operated on for hyperthyroidism between 2004 and 2012 were included in a retrospective study. Total thyro...
متن کاملThyroid cancer in patients with hyperthyroidism.
Thyroid cancer can be associated with thyrotoxicosis caused by Graves' disease, toxic multinodular goiter, or autonomously functioning thyroid adenoma. The objective of this study was to summarize current evidence regarding the association of thyroid cancer and hyperthyroidism, particularly with respect to the type of hyperthyroidism found in some patients, and whether this affects the outcome ...
متن کاملThyroid Cancer in Patients with Hyperthyroidism
▼ Thyroid cancer can be associated with thyrotoxicosis caused by Graves’ disease, toxic multinodular goiter, or autonomously functioning thyroid adenoma. The objective of this study was to summarize current evidence regarding the association of thyroid cancer and hyperthyroidism, particularly with respect to the type of hyperthyroidism found in some patients, and whether this aff ects the outco...
متن کاملCD117 Expression in Multinodular Goiter and Papillary Thyroid Carcinoma and Its Association with Prognostic Factors
Background and purpose: Multinodular goiter is a benign enlargement of thyroid gland and papillary thyroid carcinoma is the most common type of thyroid cancer. Today, immunohistochemical markers can be used in diagnosis and prognosis of tumors. The aim of this study was to compare the expression of CD117 in multinodular goiter and papillary thyroid carcinoma and its association with prognostic...
متن کاملAmiodarone-induced thyrotoxicosis with paroxysmal supraventricular (ectopic atrial) tachycardia: case report and review of the literature
The most common side effects of amiodarone therapy include disruptions of thyroid function with the incidence range from 14-18% [1, 2]. In fact this antiarrhythmic drug is rich in iodine and during common therapy the oversupply of iodine is 50-100 times higher than its optimal intake. Moreover, due to its intrinsic qualities (not related to iodine load), such as structural resemblance to thyroi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Medical principles and practice : international journal of the Kuwait University, Health Science Centre
دوره 21 2 شماره
صفحات -
تاریخ انتشار 2012